Publications - SNF Prof. Dr. Tuncay Baubec

Rodrigo Villaseñor & Tuncay Baubec

Regulatory mechanisms governing chromatin

organization and function

Current Opinion in Cell Biology

Volume 70, June 2021, Pages 10-17

Damian Dalcher, Jennifer Yihong Tan,Cristiana Bersaglieri,  Rodrigo Peña-Hernández, Eva Vollenweider, Stefan Zeyen, Marc W Schmid, Valerio Bianchi, Stefan Butz, Marcin Roganowicz, Rostyslav Kuzyakiv, Tuncay Baube, Ana Claudia Marques3 & Raffaela Santoro

BAZ2A safeguards genome architecture of

ground-state pluripotent stem cells

The EMBO Journal (2020) e105606

Ino D. Karemaker, Tuncay Baubec

DNA methyltransferases hitchhiking on chromatin

Publication Date: 24.08.2020
Swiss Med Wkly. 2020;150:w20329
PubMed Full Text Article

Rodrigo Villaseñor, Ramon Pfaendler, Christina Ambrosi, Stefan Butz, Sara Giuliani, Elana Bryan, Thomas W. Sheahan, Annika L.  Gable, Nina Schmolka, Massimiliano Manzo, Joël Wirz, Christian Feller, Christian von Mering, Ruedi Aebersold, Philipp Voigt and Tuncay Baubec

ChromID identifies the protein interactome at chromatin marks

Nat Biotechnol. 2020 Jun;38(6):757. doi: 10.1038/s41587-020-0484-5. PMID: 32518402
PubMed Full Text Article

Till Ringel, Nina Frey, Femke Ringnalda, Sharan Janjuha, Sarah Cherkaoui, Stefan Butz, Sumana Srivatsa, Martin Pirkl, Giancarlo Russo, Lukas Villiger, Gerhard Rogler, Hans Clevers, Niko Beerenwinkel, Nicola Zamboni, Tuncay Baubec, and Gerald Schwank

Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-b Resistance

Cell Stem Cell 2020 Mar 5;26(3):431-440.e8 
PubMed Full Text Article

Gustavo A. Ruiz Buendía, Marion Leleu, Flavia Marzetta, Ludovica Vanzan, Jennifer Y. Tan, Victor Ythier, Emma L. Randall, Ana C. Marques, Tuncay Baubec, Rabih Murr, Ioannis Xenarios, Vincent Dion

Three-dimensional chromatin interactions remain stable upon CAG/CTG repeat expansion

Science Advances 2020 Jul 3;6(27):eaaz4012. doi: 10.1126/sciadv.aaz4012. eCollection 2020 Jul.
PubMed Full Text Article

Manzo M, Wirz J, Ambrosi C, Villaseñor R, Roschitzki B, Baubec T
Isoform-specific localization of DNMT3A regulates DNA methylation fidelity at bivalent CpG islands
The EMBO Journal 2017, published online October 26
PubMed Full Text Article UZH press release

Ambrosi C, Manzo M, Baubec T

PubMed Full Text Article

Hiragami-Hamada K, Soeroes S, Nikolov M, Wilkins B, Kreuz S, Chen C, De La Rosa-Velázquez IA, Zenn HM, Kost N, Pohl W, Chernev A, Schwarzer D, Jenuwein T, Lorincz M, Zimmermann B, Walla PJ, Neumann H, Baubec T, Urlaub H, Fischle W
Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin
Nat Commun. 2016 Apr 19;7:11310

PubMed Full Text Article

Bartolomei G, Leutert M, Manzo M, Baubec T, Hottiger MO
Analysis of Chromatin ADP-Ribosylation at the Genome-wide Level and at Specific Loci by ADPr-ChAP
Mol Cell. 2016 Feb 4;61(3):474-485

PubMed Full Text Article

Liu CH, Finke A, Díaz M, Rozhon W, Poppenberger B, Baubec T, Pecinka A
Repair of DNA Damage Induced by the Cytidine Analog Zebularine Requires ATR and ATM in Arabidopsis
Plant Cell. 2015 Jun;27(6):1788-800

PubMed Full Text Article

Baubec T, Colombo DF, Wirbelauer C, Schmidt J, Burger L, Krebs AR, Akalin A, Schübeler D
Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation
Nature 2015 Apr 9;520(7546):243-7

PubMed Full Text Article

Baubec T, Finke A, Mittelsten Scheid O, Pecinka A
Meristem-specific expression of epigenetic regulators safeguards transposon silencing in Arabidopsis
EMBO Rep. 2014 Apr;15(4):446-52

PubMed Full Text Article

Baubec T, Schübeler D
Genomic patterns and context specific interpretation of DNA methylation
Curr Opin Genet Dev 2014 Apr;25:85-92

PubMed Full Text Article

Baubec T, Ivánek R, Lienert F, Schübeler D
Methylation-dependent and -independent genomic targeting principles of the MBD protein family
Cell 2013 Apr 11;153(2):480-92

PubMed Full Text Article

Lienert F, Mohn F, Tiwari VK, Baubec T, Roloff TC, Gaidatzis D, Stadler MB, Schübeler D
Genomic prevalence of heterochromatic H3K9me2 and transcription do not discriminate pluripotent from terminally differentiated cells
PLoS Genet. 2011 Jun;7(6):e1002090

PubMed Full Text Article

Pecinka A, Dinh HQ, Baubec T, Rosa M, Lettner N, Mittelsten Scheid O
Epigenetic regulation of repetitive elements is attenuated by prolonged heat stress in Arabidopsis
Plant Cell. 2010 Sep;22(9):3118-29

PubMed Full Text Article

Baubec T, Dinh HQ, Pecinka A, Rakic B, Rozhon W, Wohlrab B, von Haeseler A, Mittelsten Scheid O
Cooperation of multiple chromatin modifications can generate unanticipated stability of epigenetic States in Arabidopsis
Plant Cell. 2010 Jan;22(1):34-47

PubMed Full Text Article

Baubec T, Pecinka A, Rozhon W, Mittelsten Scheid O
Effective, homogeneous and transient interference with cytosine methylation in plant genomic DNA by zebularine
Plant J. 2009 Feb;57(3):542-54

PubMed Full Text Article

Rozhon W, Baubec T, Mayerhofer J, Mittelsten Scheid O, Jonak C
Rapid quantification of global DNA methylation by isocratic cation exchange high-performance liquid chromatography
Anal Biochem. 2008 Apr 15;375(2):354-60

PubMed Full Text Article

Baubec T, Mittelsten Scheid O
Medea in full self-control
Trends Plant Sci. 2006 Oct;11(10):469-71

PubMed Full Text Article

Braidotti G, Baubec T, Pauler F, Seidl C, Smrzka O, Stricker S, Yotova I, Barlow DP
The Air noncoding RNA: an imprinted cis-silencing transcript​​​​
Cold Spring Harb Symp Quant Biol. 2004;69:55-66

PubMed Full Text Article