Publications - Ass. Prof. Dr. Francisco Verdeguer

Cecilia Morgantini, Jennifer Jager, Xidan Li, Laura Levi, Valerio Azzimato, André Sulen, Emelie Barreby, Connie Xu, Michaela Tencerova, Erik Näslund, Chanchal Kumar, Francisco Verdeguer, Sara Straniero, Kjell Hultenby, Niklas K. Björkström, Ewa Ellis, Mikael Rydén, Claudia Kutter, Tracey Hurrell, Volker M. Lauschke, Jeremie Boucher, Aleš Tomčala, Gabriela Krejčová, Adam Bajgar & Myriam Aouadi
Liver macrophages regulate systemic metabolism through non-inflammatory factors
Nature Metabolism. volume 1, pages 445–459 (2019)

Hatting M, Rines AK, Luo C, Tabata M, Sharabi K, Hall JA, Verdeguer F, Trautwein C, Puigserver P
Adipose Tissue CLK2 Promotes Energy Expenditure during High-Fat Diet Intermittent Fasting
Cell Metab. 2017 Feb 7;25(2):428-437. doi: 10.1016/j.cmet.2016.12.007
PubMed Full Text Article

Lerner J, Bagattin A, Verdeguer F, Makinistoglu MP, Garbay S, Felix T, Heidet L, Pontoglio M
Human mutations affect the epigenetic/bookmarking function of HNF1B
Nucleic Acids Res. 2016 Sep 30;44(17):8097-111. doi: 10.1093/nar/gkw467
PubMed Full Text Article

Barrow JJ, Balsa E, Verdeguer F, Tavares CD, Soustek MS, Hollingsworth LR 4th, Jedrychowski M, Vogel R, Paulo JA, Smeitink J, Gygi SP, Doench J, Root DE, Puigserver P
Bromodomain Inhibitors Correct Bioenergetic Deficiency Caused by Mitochondrial Disease
Complex I Mutations
Mol Cell. 2016 Oct 6;64(1):163-175. doi: 10.1016/j.molcel.2016.08.023
PubMed Full Text Article

Verdeguer F, Soustek MS, Hatting M, Blättler SM, McDonald D, Barrow JJ, Puigserver P
Brown Adipose YY1 Deficiency Activates Expression of Secreted Proteins Linked to Energy Expenditure and Prevents Diet-Induced Obesity
Mol Cell Biol. 2015 Oct 26;36(1):184-96. doi: 10.1128/MCB.00722-15
PubMed Full Text Article

Rines AK, Verdeguer F, Puigserver P
Adenosine activates thermogenic adipocytes
Cell Res. 2015 Feb;25(2):155-6
PubMed Full Text Article

Verdeguer F, Blättler SM, Cunningham JT, Hall JA, Chim H, Puigserver P
Decreased genetic dosage of hepatic Yin Yang 1 causes diabetic-like symptoms
Mol Endocrinol. 2014 Mar;28(3):308-16. doi: 10.1210/me.2013-1173. Epub 2014 Jan 27
PubMed Full Text Article

Blättler SM, Cunningham JT, Verdeguer F, Chim H, Haas W, Liu H, Romanino K, Rüegg MA, Gygi SP, Shi Y, Puigserver P
Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling
Cell Metab. 2012 Apr 4;15(4):505-17. doi: 10.1016/j.cmet.2012.03.008
PubMed Full Text Article

Verdeguer F, Le Corre S, Fischer E, Callens C, Garbay S, Doyen A, Igarashi P, Terzi F, Pontoglio M
A mitotic transcriptional switch in polycystic kidney disease
Nat Med. 2010 Jan;16(1):106-10. doi: 10.1038/nm.2068. Epub 2009 Dec 6
PubMed Full Text Article

Blättler SM, Verdeguer F, Liesa M, Cunningham JT, Vogel RO, Chim H, Liu H, Romanino K, Shirihai OS, Vazquez F, Rüegg MA, Shi Y, Puigserver P
Defective mitochondrial morphology and bioenergetic function in mice lacking the transcription factor Yin Yang 1 in skeletal muscle
Mol Cell Biol. 2012 Aug;32(16):3333-46. doi: 10.1128/MCB.00337-12. Epub 2012 Jun 18
PubMed Full Text Article

Fisher FM, Kleiner S, Douris N, Fox EC, Mepani RJ, Verdeguer F, Wu J, Kharitonenkov A, Flier JS, Maratos-Flier E, Spiegelman BM
FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis
Genes Dev. 2012 Feb 1;26(3):271-81
doi: 10.1101/gad.177857.111
PubMed Full Text Article

Panasyuk G, Espeillac C, Chauvin C, Pradelli LA, Horie Y, Suzuki A, Annicotte JS, Fajas L, Foretz M, Verdeguer F, Pontoglio M, Ferré P, Scoazec JY, Birnbaum MJ, Ricci JE, Pende M
PPARγ contributes to PKM2 and HK2 expression in fatty liver​​​
Nat Commun. 2012 Feb 14;3:672. doi: 10.1038/ncomms1667
PubMed Full Text Article

Verdeguer F, Castro C, Kubicek M, Pla D, Vila-Caballer M, Vinué A, Civeira F, Pocoví M, Calvete JJ,
Andrés V
Complement regulation in murine and human hypercholesterolemia and role in the control of macrophage and smooth muscle cell proliferation
Cardiovasc Res. 2007 Nov 1;76(2):340-50
PubMed Full Text Article